Vacation Homes in Southeast Missouri, MO

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Top Vacation Homes in Southeast Missouri

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top hotels in Southeast Missouri

Southeast Missouri Vacation Home Rentals

What kind of vacation do you want in Southeast Missouri? The answer to that question will help you choose the right lodging for your stay. The wise wanderer knows that a vacation home is an essential part of the traveling experience. It’s more than just a place to crash at night—it’s where you wake up in the morning, where you lounge when you’re not exploring, and it’s the starting point for all your adventures. No matter what type of vacation homes strike your fancy, Travelocity has something in Southeast Missouri that will speak to you.

Do you want a fully equipped kitchen so you can exercise your culinary mastery and impress your travel buddies? How about a romantic terrace for your anniversary trip? Have you always wished to fall asleep to the sound of waves crashing on the shore? One of our vacation home rentals is bound to add that extra magic to your trip. In fact, we’ve got plenty of options lined up just for you in Southeast Missouri, including luxury vacation home rentals. On a budget? We can work with your funds and still give you a great place to sleep at night.

Take a look at what we have on offer. You’ll find rental houses close to the big tourist draws, as well as rentals that keep you away from the crowd. Consider vacation homes a little off the beaten path where you can live like a local and discover hidden gems that never make it to the tourist sites. Book through Travelocity and start your getaway today.

Southeast Missouri Vacation Homes essential information

Accommodation
139 Vacation Homes
Lowest Price
$57
Highest Price
$159
Popular accommodation
"Little Brick House on Main (1865)”, Dexter Homestead. VERY Cozy & Clean 7 Bed home., Unique cabins in the woods
Not friendly for Street Bikes. Beautifulin FALL!, Serenity South -- Gardens, River-Views, and Refreshing Space, Cozy Three bedroom home in Central Farmington, Modern 3br Gem in Heart of Ironton, Quiet, Cozy Cabin!, Newly remodeled offers many amenities with perfect location!, RIVER FRONT HOUSE, The 1801 House: A beautiful historic home in the Ste Genevieve Historic District, Newly renovated early 1900’s farmhouse, Cozy Barn Loft in Farmington, Missouri